Missouri Casserole Beef Cheese

Featured in: Supper Club Comforts

Missouri Casserole combines savory ground beef, kidney beans, and sweet corn, layered with salsa and crowned with melty cheddar cheese. This easy-to-prepare dish captures the comforting spirit of the Midwest and is perfect for casual dinners or potlucks. Prep the filling on the stove, top with cheese (and optional tortilla chips or cornbread), then bake until hot and golden. Customize it by adding black beans, bell peppers, or a dollop of sour cream for extra flavor and texture. Serve warm, scooping generous helpings straight from the baking dish.

Updated on Sat, 30 Aug 2025 08:17:31 GMT
A plate of food with a slice of chicken and cheese. Save to Pinterest
A plate of food with a slice of chicken and cheese. | buddybiteskitchen.com

This Missouri casserole has all the flavors you want from Midwest comfort food: juicy ground beef, hearty beans, golden corn, and a gooey blanket of cheddar. I love how it comes together with very little fuss and makes the kitchen smell like home on chilly nights.

I made this the first winter after I moved to Missouri and was amazed by how something so simple could become a fast favorite. It is now our go-to when friends stop by or anyone needs a little extra comfort.

Ingredients

  • Ground beef: brings savory richness and classic casserole texture go for leaner if you want less grease
  • Onion: adds sweetness and depth choose fresh firm onions for the strongest flavor
  • Garlic: infuses warmth and complexity always use fresh cloves for best aroma
  • Kidney beans: boost protein and fiber plus their color pops beautifully rinse canned beans well
  • Corn: offers sweetness and juicy bites frozen or canned corn both work well so use whichever you like
  • Salsa or diced tomatoes: create the tangy saucy base chunky salsa makes it lively
  • Shredded cheddar cheese: melts perfectly for that classic Midwest topping buy a brick and shred it yourself for the best melt
  • Crushed tortilla chips or cornbread crumbles (optional): add crunch and extra heartiness homemade or store bought both do the trick

Instructions

Preheat and Prepare:
Set your oven to 375 degrees Fahrenheit or 190 degrees Celsius. Give it a good ten minutes to really come up to temperature. Meanwhile place a large skillet over medium heat.
Brown the Beef and Aromatics:
Add the ground beef to your skillet with diced onion and minced garlic. Stir regularly and break up the beef as it cooks. Take your time here make sure the beef is deeply browned and the onion is completely soft and golden at least eight to ten minutes. This layering step is what gives the finished casserole a savory backbone.
Add Beans Corn and Salsa:
Once your beef is browned turn the heat down to medium low. Add in the drained kidney beans and corn followed by the salsa or diced tomatoes. Stir everything together so it is evenly mixed. Let it simmer together for about five minutes to meld the flavors and evaporate a bit of moisture.
Assemble in Baking Dish:
Pour your beef and bean mixture into a baking dish eight by eleven or nine by thirteen inches both work. Use a spatula to spread it into an even layer all the way to the edges. Sprinkle the shredded cheddar cheese evenly over the top. If you want extra crunch toss on a handful of tortilla chips or some cornbread crumbles.
Bake to Perfection:
Slide your casserole on the middle oven rack and bake for fifteen to twenty minutes. The cheese should be bubbly and just turning golden at the edges. Remove from the oven and let rest five minutes before scooping.
A delicious looking meal with a fork and knife. Save to Pinterest
A delicious looking meal with a fork and knife. | buddybiteskitchen.com

What always stands out to me is the way cheddar cheese bubbles and browns on top. The kids love scraping the baked cheese from the sides. This was the first dish I ever made for a Missouri potluck and I have come to crave that hearty cheesy crust.

Storage Tips

Let the casserole cool completely before covering and refrigerating in an airtight container. It keeps well for up to three days and the flavors deepen over time. Warm individual servings in the microwave or the whole dish in a moderate oven loosely covered with foil.

Ingredient Substitutions

You can swap black beans or pinto beans in place of kidney beans and use ground turkey instead of beef for a lighter feel. Fresh or canned diced tomatoes both work and pepper jack cheese brings a little kick if you want more spice.

Serving Suggestions

Serve with a spoonful of sour cream and fresh sliced jalapeños if you like heat. A crisp green salad on the side lightens things up. I have even ladled the casserole over baked potatoes or tucked spoonfuls into tortillas for a next day lunch.

Cultural Context

Hearty casseroles like this are a staple of Midwest gatherings and potlucks. They make the most of pantry goods and come together with minimal fuss perfect for feeding large groups during busy farm seasons or small town events.

Seasonal Adaptations

In summer stir in some fresh bell pepper for color. Use roasted corn and garden tomatoes when they are in season. Substitute ground venison or pork if you have it after hunting season.

Success Stories

One winter my neighbor dropped off a pan of Missouri casserole while I was under the weather and to this day I pay it forward whenever someone in my circle needs a little home cooked comfort.

Freezer Meal Conversion

Assemble the casserole up to the point of baking then wrap tightly in foil and freezer safe wrap. Freeze for up to three months. Bake straight from frozen at 350 degrees for thirty five to forty five minutes covered then another ten uncovered to brown the cheese.

A plate of food with a slice of chicken and cheese. Save to Pinterest
A plate of food with a slice of chicken and cheese. | buddybiteskitchen.com

This casserole is everything you need on a chilly evening: hearty, cheesy, and effortless. It will become an instant classic in your recipe lineup.

Common Recipe Questions

Can I substitute the ground beef?

Yes, ground turkey or chicken works well, or try meatless crumbles for a vegetarian alternative.

What toppings add extra crunch?

Crushed tortilla chips or cornbread crumbles add texture and enhance the casserole’s flavor when baked on top.

Is this casserole freezer friendly?

Yes, assemble and bake, then cool completely before freezing in an airtight container. Reheat before serving.

How can I add more flavor?

Try mixing in diced bell peppers, extra spices, or a drizzle of sour cream after baking.

What sides pair well with this dish?

Fresh salads, green beans, or warm bread complement the casserole’s hearty flavors.

Missouri Casserole Beef Cheese

Ground beef, beans, corn, and melty cheese bake up for a Midwest-inspired comfort food classic.

Prep Time
20 minutes
Cook Time
35 minutes
Total Time
55 minutes
Created By Max Buddyfield

Recipe Category Supper Club Comforts

Skill Level Easy

Cuisine Type American

Recipe Yield 6 Number of Servings

Dietary Preferences Free of Gluten

What You'll Need

Base

01 1 pound ground beef
02 1 onion, diced
03 2 garlic cloves, minced
04 1 can (15 ounces) kidney beans, drained and rinsed
05 1 can (15 ounces) corn, drained
06 1 cup salsa or diced tomatoes

Topping

01 1 cup shredded cheddar cheese
02 Crushed tortilla chips or cornbread crumbles, optional

Steps to Follow

Step 01

Preheat and Sauté: Preheat oven to 375°F. In a large skillet over medium heat, cook ground beef, diced onion, and minced garlic until the beef is browned and onion is soft.

Step 02

Combine and Simmer: Add drained kidney beans, drained corn, and salsa or diced tomatoes to the skillet. Stir well and simmer for 5 minutes.

Step 03

Assemble: Transfer the beef mixture into a baking dish. Evenly top with shredded cheddar cheese and, if desired, sprinkle crushed tortilla chips or cornbread crumbles over the cheese.

Step 04

Bake: Bake in the preheated oven for 15 to 20 minutes, until the cheese is melted and the casserole is bubbling.

Tools You'll Need

  • Skillet
  • Baking dish

Allergy Warnings

Review each ingredient carefully for allergens. If unsure, consult with a healthcare provider.
  • Contains dairy from cheddar cheese.

Nutritional Info (per serving)

These details are for general information only. Always consult a healthcare professional for dietary concerns.
  • Calorie Count: 480
  • Fat Content: 22 grams
  • Carbohydrates: 35 grams
  • Protein Content: 30 grams